Examining two independent PCa clinical datasets [GSE3325 (Varambally et al, 2005) (Data ref: Varambally et al, 2005) and GSE3933 (Lapointe et al, 2004) (Data ref: Lapointe et al, 2004)], we also showed that PLXND1 mRNA levels were uniformly upregulated in cancer compared with normal tissue (Fig. 2C). The gene discussed is PLXND1; the disease is cancer.