For example, the B-type plexins, which are the best studied in PCa, are overexpressed in PCa and context-dependently promote PCa growth, metastasis, chemoresistance, and AR/GR nuclear translation in response to Sema3C or Sema4D (Garg et al, 2023; Li et al, 2020; Peacock et al, 2018; Shorning et al, 2023; Williamson et al, 2019; Wong et al, 2007). This evidence concerns the gene SEMA4D and posterior cortical atrophy.