An analysis of data from the TCGA database revealed that the expression level of lnc-CHAF1B-2 was upregulated in 19 different types of cancer, including bladder cancer, breast cancer, cervical squamous cell carcinoma, colon cancer, oesophageal cancer, liver cancer, lung cancer, and gastric cancer, as shown in Fig. 1A. To investigate the biological effects of lnc-CHAF1B-2 in gastric cancer, we analysed its expression in gastric cancer tissues and their corresponding adjacent noncancerous tissues. Here, CHAF1B is linked to carcinoma of esophagus.