TSPO and myeloid sarcoma: A clinical study in healthy subjects revealed the high specific uptake of [18F]PBR111 in human brains of various ages and genetic groups, thus demonstrating its ability to quantify the TSPO expression level in humans.392 [18F]PBR111 has also been applied to assess neuroinflammation in the white matter of multiple sclerosis (MS) brains, thus confirming the feasibility of [18F]PBR111 for characterizing the immune responses of MS patients.393