[68Ga]Ga-DOTA-CPCR4-2 (Pentixafor) exhibited high affinity for targeting CXCR4 (the IC50 value of [natGa]Ga-DOTA-CPCR4-2 was 4.99 ± 0.72 nM).152 Recently, Dreher et al. performed CXCR4-directed PET/CT using [68Ga]Ga-Pentixafor in 142 patients with histologically confirmed tumours, including 23 solid tumours. The gene discussed is CXCR4; the disease is neoplasm.