A subsequent clinical trial (NCT05321316) was conducted to investigate the ability of [68Ga]Ga-N188 to detect Nectin-4 upregulation in patients with urothelial carcinoma, particularly in patients with recurrent or advanced bladder cancer; the results confirmed that [68Ga]Ga-N188 can be used as an efficient PET tracer for imaging Nectin-4.246. Here, NECTIN4 is linked to urinary bladder cancer.