Classical fibrotic mediators and markers (including Tgfb1, Timp1, and Vcam1), collagen of the ECM (including Col4a1, Col4a2, Col16A1, and Col18a1) and cell surface adhesion and signaling integrin (Itga2, Itga5) were found to be differentially expressed in the enriched hepatic fibrosis pathways (Appendix Fig. S2). This evidence concerns the gene ITGA2 and Hepatic fibrosis.