MYC and Lymphadenopathy: At four weeks of age, neither Eμ-myc Casp1−/−Casp11−/− nor Eμ-myc mice showed any signs of lymphadenopathy (Fig. 1a) or appearance in the blood of large blast-like cells (Fig. 1b), features characteristic of the malignant stages of disease in Eμ-myc mice (Fig. 1a,b malignant panels and Extended Data Fig. 1d).