Consistent with the recruitment of monocytes from the periphery, imaging of WT and IFNγRKO tumours revealed that Ly6C+ cells resided in or near CD31+ blood vessels, which were found either within the core of the tumour, or at the margin, surrounding the tumour (Fig. 5F and Supplementary Fig. 5E, F). The gene discussed is PECAM1; the disease is neoplasm.