OVA-specific CD8+ T cells expressed GFP to a greater extent than the tetramer-negative CD8+ T cells in both WT and H2-Kb/Db KO tumours (Supplementary Fig. 2K), confirming that the microenvironment is critically important to support CD8+ T cells priming and most likely their maintenance/expansion. The gene discussed is CD8A; the disease is neoplasm.