CAMK2G and heart failure: ISO infusion also induced a marked increase in the expression of two proteins that are well established to be associated with maladaptive cardiac hypertrophy and heart failure (Anderson et al., 2011; Sheng et al., 2016), including sarcomeric protein, α‐actinin (Figure 3f,g), and the serine–threonine kinase, Ca2+‐/calmodulin‐dependent protein kinase II (CaMKII; Figure 3f,h).