Furthermore, our findings challenge the prevailing view that ALKBH5 is primarily an m6A demethylase, as its demethylase activity has been predominantly reported when it is upregulated in cancer, although several studies have also demonstrated its demethylase function also in noncancer research (Yu et al. 2020; Gao et al. 2023). The gene discussed is ALKBH5; the disease is cancer.