临床特征:86例患者中,男45例(52.3%),女41例(47.7%),中位年龄42(14~78)岁。59例(68.6%)为B细胞急性淋巴细胞白血病(ALL),27例(31.4%)为非霍奇金淋巴瘤(NHL)(弥漫大B细胞淋巴瘤22例,伯基特淋巴瘤3例,套细胞淋巴瘤2例)。38例(44.2%)患者接受CD19单靶点CAR-T细胞治疗,48例(55.8%)患者接受CD19和CD22双靶点CAR-T细胞治疗。. This evidence concerns the gene CD19 and acute lymphoblastic leukemia.