INS and cardiovascular disorder: These effects might also be translated to otherclinical settings including cardiovascular diseases.894 The effect of chromium on amplifying insulin signalingalso represents a promising line of research for the treatment ofdiabetes.895−897 Other small molecules that affect insulin-resistancein vitro including chromium complexes have been documented897−899 (Table 12) and represent an interesting starting point for thedevelopment of therapeutic strategies.