Hepcidin itself is regulatedby bone morphogenetic protein 6 (BMP6), which is also regulated byiron levels via the TF nuclear factor erythroid 2-related factor 2(NRF2).468 Furthermore, iron-containingferritin can be exported from cells.469 In line with this, Prominin2 has been implicated in the regulationof lipid dynamics and can promote the formation of ferritin-containingmultivesicular bodies (MVBs) and exosomes to export cellular ironfrom mammary epithelial and breast carcinoma cells. This evidence concerns the gene BMP6 and breast carcinoma.