We infected A549 cells with the WT and ∆PTM viruses and assessed the interaction between protein VII and E1A by IP at 24 h p.i. In contrast to our B2H results, we observed that E1A robustly co-immunoprecipitated with WT protein VII, indicating the two proteins interact in cells during infection (Fig. 8B). Here, DHTKD1 is linked to infection.