In addition, the induction of IFN-λ1 mRNA was significantly weaker in response to infection with the Pheasant/21 isolate as compared to the Human/04 isolate (p < 0.05, 95% confidence interval (CI) 0.37 × 105 to 2.97 × 105, Supplementary Table 2). The gene discussed is IFNL1; the disease is infection.