Indeed, MC.7.G5 and MC.27.759S clones killed MR1*01-homozygous cancer cells ES-5838, RD-ES, and FM72 to levels seen with A549 cells (Figure 2A), which are MR1*01/*04, so our results do not support assertions that the MC.7.G5 TCR, or other TCRs, target cells via an allogenic reaction with the rare MR1*04 variant carried by approximately 0.8% of the population (15). This evidence concerns the gene MR1 and cancer.