PIM1 and atherosclerosis: In addition, the oil red O staining revealed more minor lipid lesions in the aortic root and carotid artery in ApoE-/--Endo-Pim1KD mice than in ApoE-/--Control mice (Figure 5B-D), Also, Masson staining showed Pim1 knockdown increased the content of collagen and the ratio of fibrous cap in the aortic root and carotid artery atherosclerosis plaques (Figure 5C-D; Figure S10A-B).