After performing immunofluorescent (IF) co-staining with the marker P2RY12 in samples from patients with glioma, we identified that the cells that expressed S100A13 corresponded to microglia (Figure 3E-F), capable of actively contributing to the neuroinflammation of the GBM due to their location in the leading edge of the tumor. This evidence concerns the gene S100A13 and glioblastoma.