Anti-GD1b (serum and CSF) and anti-GM1 immunoglobulin G (IgG) (serum) were positive in one patient with AMSAN, anti-NF186 IgG (serum and CSF) was positive in one patient with AIDP, and anti-GM4 IgG, anti-MAG IgM (serum) and anti-GD3, anti-GD2 IgG (CSF) were positive in one patient with CIDP. The gene discussed is CD40LG; the disease is Guillain-Barre syndrome, familial.