The results revealed that patients with elevated MyD88 expression exhibited higher enrichment of Hallmark pathways such as "UNFOLDED_PROTEIN_RESPONSE,""IL2_STAT5_SIGNALING","PROTEIN_SECRETION," (Fig. 2E), as well as KEGG gene sets including "Adherens junction," "Arrhythmogenic right ventricular cardiomyopathy ARVC," and "Endocytosis" (Fig. 2F). Here, MYD88 is linked to Arrhythmogenic right ventricular dysplasia.