Survival analysis revealed that circMVP expression was associated with poor survival (P = 0.0009, Fig. 8E), and high expression of METTL3 (P = 0.0054) and B7-H3 (P = 0.0184) also suggested a poor prognosis in TCGA CRC patients (Fig. S6E and Fig. S6F). The gene discussed is CD276; the disease is colorectal carcinoma.