In esophageal squamous cell carcinoma (ESCC), tRF-3024b, which upregultes in ESCC cells that survived co-culture with cytotoxic T lymphocytes (CTLs), has been shown to reduce tumor cell apoptosis by sequestering miR-192-5p and promoting BCL-2 expression, thereby enhancing the protective effects of BCL-2 107. This evidence concerns the gene BCL2 and neoplasm.