In addition, Patients with G-CSF-induced aortitis of these four types were similar in clinical manifestations, such as fever, chest pain, abdominal pain, neck pain, back pain, earache, sore throat, headache and myalgia, etc. Meanwhile, the four types of G-CSF-induced aortitis also exhibited similarities in their common occurrence sites, all of which were prone to occur in the aortic arch, abdominal aorta, and thoracic aorta, etc. Here, CSF3 is linked to aortitis.