The average change in the serum concentration of the anti-inflammatory IL-10 between the pre-and postoperative samples increased by 1.07 units among participants with DSF with underlying significant extra-axial hemorrhage compared to those with DSF without underlying significant extra-axial hemorrhage (aCoef, −1.07, 95%CI, −2.02: −0.10, p = 0.05). The gene discussed is IL10; the disease is hemorrhage.