Regulation of FTO levels was observed in MI and heart failure (HF) patients and corresponding animal models (Mathiyalagan et al., 2019; Shi et al., 2021; Zhang et al., 2021a; Zhang et al., 2021b; Hinger et al., 2021; Wen et al., 2022; Wang X. et al., 2022; Vausort et al., 2022; Liu et al., 2022). This evidence concerns the gene FTO and myocardial infarction.