SNAI1 and lip and oral cavity carcinoma: It has been shown that periodontal bacteria modulate EMT phenotype in oral cancer cells by upregulating the expression of metalloproteinases (MMP-9, MMP-1, MMP-2, MMP-10)29,34, transcription factors (STAT-3, ZEB-1, MYC, Snail)32 and downregulating the expression of epithelial markers (E-cadherine, Cytokeratine 13)33.