Bulk RNA sequencing of patient tumours with a predominant CAF‐S1 phenotype show an upregulation of CCL2, CCL3, CCL4, CXCL9, CXCL10, CXCL11, CXCL12, IL1RN, IL6 and LIF, compared to CAF‐S4 which reflects a myCAF phenotype. The gene discussed is IL6; the disease is neoplasm.