We have previously shown that activated T cells induce major histocompatibility complex (MHC) II expression and upregulate CD73 expression as well as IL6 and IL27 secretion in NSCLC CAFs in vitro via IFNγ and TNFα, reminiscent of the newly identified interferon‐licenced fibroblast [6, 7]. This evidence concerns the gene TNF and non-small cell lung carcinoma.