PC and breast carcinoma: 39S ribosomal protein L34 was identified as a risk factor for breast cancer (IVW, p=0.021, OR = 1.069, 95% CI: 1.010–1.132), while pyruvate carboxylase showed a causal association with breast cancer as a risk factor (IVW, p=0.007, OR = 1.071, 95% CI: 1.019–1.127).