Related literature reported that in liver cancer patients who respond to immunotherapy, there is a cell triad: CXCL13+CD4T cells and PDCD1+CD8T cells surround mregDCs, whereas there are no Treg cells in this area, suggesting that mregDC can play a role in positively regulating immunity in the liver cancer immune microenvironment [14]. The gene discussed is CXCL13; the disease is liver cancer.