The expression of activating receptors on these A+C+ NK cells correlates with their function against tumor targets with the cognate ligands: increased degranulation and IFNγ production against the NK-sensitive K562 and 721.221 lines, and intermediate response to ADCC of BE(2)n cells labeled with anti-GD2 antibody (Supplementary Figure S1D). This evidence concerns the gene IFNG and neoplasm.