TNFSF13B and systemic lupus erythematosus: Currently, there is no cure for SLE and existing treatments such as glucocorticoids, antimalarials and monoclonal antibodies such as belimumab (blocks the B-lymphocyte stimulating factor BLyS/BAFF) or anifrolumab (inhibits the interferon type 1 receptor -IFNAR1-) are insufficient for controlling the disease.