Other studies implicated MYC, a well-characterized TF with strong oncogenic potential, in the transcriptional regulation of CD47 during the progression of leukemia using MYC-induced T cell acute lymphoblastic leukemia mouse model; MYC T-ALL, and human leukemia cells lines; CCRF-CEM and Jurkat (16). This evidence concerns the gene MYC and acute lymphoblastic leukemia.