Interestingly, binding sites for MYC TF were also identified in our analysis of CD47 proximal promoter region (Supplementary Figure 3A), however, MYC binding was undetectable in human malignant melanoma within CD47 DNA promoter region between -120bp to +54 relative to TSS required for its activation (Supplementary Figure 3B). The gene discussed is TF; the disease is melanoma.