A higher proportion of inpatients wereclassified as NYHA class IV and presented with elevated NT-proBNP levels.Although the use of triple anti-HF drugs was more prevalent among inpatientscompared with outpatients, the utilization of SGLT2I was lower, resulting insimilar rates of quadruple anti-HF drug therapy between the two groups. This evidence concerns the gene NPPB and hydrops fetalis.