Results: GRB7 expression was significantly upregulated in bladder urothelial carcinoma (BLCA), cervical squamous cell carcinoma (CESC), cholangiocarcinoma (CHOL), colon adenocarcinoma (COAD), rectum adenocarcinoma (READ), thyroid carcinoma (THCA), and uterine carcinosarcoma (UCEC). Here, GRB7 is linked to rectum adenocarcinoma.