Indeed, CCR2+ monocytes have been reported to reduce brain injury, lower inflammation and promote repair in the brain after cerebral ischemia (Chu et al., 2015; Pedragosa et al., 2020; Miró-Mur et al., 2016; Fang et al., 2018; Wattananit et al., 2016). Here, CCR2 is linked to Cerebral ischemia.