RREB1 and melanoma: A study by Gerami et al identified a panel of probes for 6p25 (RREB1), 6q23 (MYB), 11q13 (CCND1) and centromere 6 (CEP6) when used in combination assisted in differentiating between melanomas and naevi with a sensitivity of 86.7% and specificity of 95.4% [11].