MUC16 and ovarian neoplasm: The selection of OC target sites has focused on molecules present on the surface of tumor cells, including glycosylated proteases linked to the inhibition of ovarian tumor cell invasion and metastasis (11), OC blood markers (12) (such as mucin 16 [MUC16] and human epididymis protein 4 [HE4]), and anti-angiogenic receptors (13) (such as vascular endothelial growth factor [VEGF] and epidermal growth factor receptor [EGFR]).