Some prior studies have suggested that patterns of tau PET uptake in LBD may be distinct from the typical Alzheimer’s disease Braak staging pattern, with higher signal in posterior temporoparietal and occipital cortex and reduced medial temporal signal relative to unimpaired controls,15-17 although other studies have not observed this pattern.12,13,18 Our data did not support the hypothesis of a unique spatial pattern of tau deposition in LBD relative to Alzheimer’s disease, with no significant difference in precuneus and lingual gyrus SUVR between LBD and healthy controls. This evidence concerns the gene MAPT and Alzheimer disease.