Many studies of tau PET in large cohorts of cognitively unimpaired older adults and impaired individuals with Alzheimer’s disease have found that greater tau PET in the temporal lobe is associated with memory performance.51,52 In this study of participants with LBD, we observed no significant association with memory for tau in entorhinal cortex or inferior temporal lobe. The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.