Previous studies have shown that GLP-1 receptors are expressed in EAT (epicardial adipose tissue) - critically involved in the development and progression of CAD, atrial fibrillation, and heart failure—and are directly correlated with genes promoting FFA (free fatty acid) oxidation and inversely with pro-adipogenic genes (21, 22). The gene discussed is GLP1R; the disease is coronary artery disorder.