All the patients were treated with low-dose aspirin (100 mg/day) in accordance with guideline recommendations and had G6PD activity measured.5 The prevalence of G6PD deficiency was 9% (56 patients), with severe G6PD deficiency being detected in 7% (n = 32) of males and in 0.6% (n = 1) of females (P < 0.001).5 Over a follow-up of 18 ± 9 months, adherence to aspirin was 100% and was not associated with aspirin-induced clinically relevant haemolysis.5 One patient died from sepsis and multiorgan failure with possible drug-related haemolysis not related to aspirin.5 This evidence concerns the gene G6PD and G6PD deficiency.