IFNG and cerebral small vessel disease: B. intestinihominis was associated with cerebral small vessel disease[42] and metastatic renal cell carcinoma.[43] Oral administration of B. intestinihominis resulted in accumulation in the colon and promoted the infiltration of IFN‐γ‐producing γδT cells in cancer lesions.[44] In general, these studies raised the possibility that B. intestinihominis might be important for the establishment of beneficial gut microbiota.