Similar to clinical samples, TNBC cell lines HCC38, HCC1806, HCC1937, Hs578T., MDA-MB231, MDA-MB468 and MDA-MB453 exhibited a relatively higher levels of GRK6 as compared to non-tumor mammary cell lines H1845F5 (H184) and MCF10A and ER + cell lines MCF7, T47D and BT-20 (Fig S2). Here, ESR1 is linked to neoplasm.