F2 and End Stage Liver Disease: The clinical characteristics of all the subjects before and after the surgery indicated that in addition to significantly increased white blood cell (WBC) and platelet (PLT) counts after splenectomy, liver function and coagulation-related indicators, such as model for end-stage liver disease (MELD) scores, albumin levels, the prothrombin time (PT), and the international normalized ratio (INR), were also markedly improved (Table 1).