CD1A and Langerhans cell histiocytosis: Histopathologic examination revealed a neoplasm characterized by sheets of ovoid cells with abundant eosinophilic cytoplasm and indented reniform nuclei with few mitotic figures, no necrosis and admixture of other inflammatory cells including lymphocytes, eosinophils, neutrophils, mast cells and neoplastic cells are positive for CD1a, S100, CD68 with low proliferative index and negative for GFAP, Synaptophysin and consistent with the diagnosis of LCH (Fig. 4 A, B and C).