In agreement with the above-mentioned, NEAT1 knockdown made an inhibition effect on the ferroptosis damaging of 6-OHDA (Fig 7I and 7K–7O), which suggests that the potential correlation between NEAT1 and ferroptosis in PD and NEAT1/miR-7b-5p/S100A2 axis might participate in PD pathogenesis. This evidence concerns the gene NEAT1 and Parkinson disease.