There was no correlation between selected biomarkers and age in IC/BPS patients (S1 Table), however, the normalized levels of MMP9 positively correlated with age in controls (Spearman’s r = 0.677, 95% CI from 0.150 to 0.905, p = 0.0182; S2 Table). This evidence concerns the gene MMP9 and Bartsocas-Papas syndrome 1.