Patients with IC/BPS had significantly higher median normalized concentrations of chemokines CCL5 (p = 0.0005), CCL11 (p = 0–0045), CXCL10 (p = 0.0007), cytokine IL4 (p = 0.0205), and BAFF (p = 0.0387) compared to controls. Here, IL4 is linked to Bartsocas-Papas syndrome 1.