The mRNA expression of CD206 and CD163, known as markers of M2 macrophages, as well as the expression of mRNA MMP12, were examined in normal uncinate process (UP), CRS without nasal polyp (CRSsNP) UP, CRS with nasal polyp (CRSwNP) UP, and CRSwNP NP tissues. The gene discussed is CD163; the disease is nasal cavity polyp.