Next, we used different energy stress inducers to treat SLC7A11‐high tumor cells and found that glutamine (Gln) starvation could induce cleavage of PARP in UMRC6 and H460 cells, and phenformin (Phe) could induce cleavage of caspase‐3 and PARP in UMRC6 cells (Figure 1F). This evidence concerns the gene SLC7A11 and neoplasm.