EPHA1 and cancer: For example, the membrane-boundprotein Ephrin, known for its role in cell adhesion and migration,has been implicated in cancer, with EphA1 being particularly associatedwith lung and lymph node metastasis.78 Additionally,actin is critical for cellular structural support, and when releasedfrom dying cells, it is recognized by the DNGR-1 receptor as a DAMP.79 In addition, ubiquitin is a heat-stable proteinwith important regulatory functions in eukaryotic cells, mainly promotingthe degradation of intracellular proteins.