IL1B and neoplasm: Together with the data obtained from the administration of IL-1β alone (Fig. 4c) and in line with previous studies employing several electroporations55,56, we find that single electroporation of cytokine-encoding plasmid is not sufficient to achieve antitumor effect that could lead to a progressive tumor volume decrease and eventual eradication, suggesting that in this experimental setting, induction of pyroptosis is crucial for achieving tumor growth control.