We profiled three murine cancer cell lines: B16F10 (melanoma), 4T1 (breast cancer) and CT26 (colon cancer) for the expression of cell death effector gasdermin D (Supplementary Fig. 1a), and the components of NLRP3 inflammasome (Supplementary Fig. 1b). This evidence concerns the gene NLRP3 and malignant colon neoplasm.