Some studies have shown different genomic landscapes in extranodal DLBCL; for instance, CNS or testicular DLBCL has the MYD88 mutation [44, 45], and breast DLBCL shows t(14;18)(q32;q21) translocation involving MALT1 and IGH [46]. The gene discussed is MYD88; the disease is diffuse large B-cell lymphoma.