IFNA1 and Dravet syndrome: Several lines of evidence support the notion that IFN hyperactivity and downstream JAK/STAT signaling are key drivers of immune dysregulation in DS (Sullivan et al., 2016; Sullivan et al., 2017; Waugh et al., 2019; Araya et al., 2019; Powers et al., 2019; Tuttle et al., 2020; Chi et al., 2023; Galbraith et al., 2023; Waugh et al., 2023).