Individuals with history of tricuspid valve regurgitation display higher rates of four different autoantibodies, most prominently against WARS1, a tryptophan tRNA synthetase mutated in various neurodevelopmental disorders (Lin et al., 2022), and SRP68, a protein commonly targeted by autoantibodies in necrotizing myopathies (Allenbach et al., 2020, Figure 1—figure supplement 1g). Here, SRP68 is linked to neurodevelopmental disorder.