The common TMs currently used for diagnosing benign and MA include carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), carbohydrate antigen 125 (CA125), carbohydrate antigen 19-9 (CA19-9), etc. CEA is a broad-spectrum tumor marker when its level is >15 μg/L (32), which prompts MA. Here, CEACAM5 is linked to microtia.